Characterization of brain networks using functional magnetic resonance imaging (fMRI) has primarily been advanced by resting-state research; however, using task-based research, functional characterizations can be more robustly determined by observing how the timing of subject-specific network-level evoked hemodynamic responses (HDRs) differ between task conditions. To this end, our laboratory has consistently applied the following principle for analysis of fMRI data: (1) isolation of task-related variance prior to network extraction; (2) network extraction though multidimensional analysis methods; (3) inclusion of all available brain areas; (4) data-driven explorations of HDR shapes.
Based on the experimental conditions to which they respond, a general cognitive function can be assigned to a small set of networks that replicate over tasks. This has also allowed observation of how specific task- driven brain networks relate to in-scanner performance, neuropsychological test scores, and symptoms of mental illness.
Bio:
Dr. Todd Woodward is a Professor in the Department of Psychiatry at UBC, Research Scientist at BC Mental Health and Substance Use Services (BCMHSUS) Research Institute, Director of the UBC Cognitive Neuroscience of Schizophrenia Laboratory (CNoS), and Principal Investigator of the UBC Brain Dynamics Laboratory. He has been instrumental in identification of task-based brain networks, and development of a novel treatment for delusions in schizophrenia though group-facilitated experiences of everyday thinking biases. To date Dr. Woodward has published over 180 peer-reviewed research manuscripts.
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2022-10-20T16:00:002022-10-20T17:00:00Task-Based Brain Networks Detectable by fMRIEvent Information:
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Abstract:
Characterization of brain networks using functional magnetic resonance imaging (fMRI) has primarily been advanced by resting-state research; however, using task-based research, functional characterizations can be more robustly determined by observing how the timing of subject-specific network-level evoked hemodynamic responses (HDRs) differ between task conditions. To this end, our laboratory has consistently applied the following principle for analysis of fMRI data: (1) isolation of task-related variance prior to network extraction; (2) network extraction though multidimensional analysis methods; (3) inclusion of all available brain areas; (4) data-driven explorations of HDR shapes.
Based on the experimental conditions to which they respond, a general cognitive function can be assigned to a small set of networks that replicate over tasks. This has also allowed observation of how specific task- driven brain networks relate to in-scanner performance, neuropsychological test scores, and symptoms of mental illness.
Bio:
Dr. Todd Woodward is a Professor in the Department of Psychiatry at UBC, Research Scientist at BC Mental Health and Substance Use Services (BCMHSUS) Research Institute, Director of the UBC Cognitive Neuroscience of Schizophrenia Laboratory (CNoS), and Principal Investigator of the UBC Brain Dynamics Laboratory. He has been instrumental in identification of task-based brain networks, and development of a novel treatment for delusions in schizophrenia though group-facilitated experiences of everyday thinking biases. To date Dr. Woodward has published over 180 peer-reviewed research manuscripts.Event Location:
Hebb 114
