UBC Physics and Astronomy is involved in a broad range of medical physics research in the areas of radiation therapy, medical imaging, biomedical optics and radiation biophysics.

Radiation Therapy

Radiation TherapyThe ultimate aim of our research in radiation therapy group at BC Cancer is to develop more accurate and effective treatments in radiation medicine, primarily in cancer treatment but with applications in other areas of medicine as well. The primary research focus is on development of innovative treatment delivery solutions using linear accelerators for MV x-rays and electrons, particle accelerators for protons or heavy ions, as well as radio-isotopes.  We also seek to develop new ways to improve the precision and accuracy of radiation dose measurement and simulation in complex clinical scenarios. Monte Carlo simulation techniques, artificial intelligence and deep learning are integral to this area of research.  Medical imaging modalities including MRI, x-ray CT, PET, SPECT, ultrasound also play a large role in advancing our research in radiation medicine.


Medical Imaging

The SPECT imaging machineMembers of the department are actively researching a variety of medical imaging techniques. A number of groups work on Magnetic Resonance Imaging. They investigate MR contrast mechanisms, develop advanced MR techniques, and carry out clinically applied MR research studies. MRI research is facilitated by having access to state-of-the-art MRI scanners at UBC MRI Research Centre. The Positron Emission Tomography (PET) research group works on technique development with a clinical focus on neurodegeneration. The Nuclear Medicine Imaging group (Quantitative Tomography Lab) focuses on quantitative PET and SPECT imaging towards improved diagnosis, prognosis, treatment response assessment and dosimetry especially in cancer patients.


Biomedical Optics

Cancer ImaginingThe cancer imaging group at the BC Cancer Research Centre exploits the interaction of light at both the micro- and macro-scopic level to detect, delineate, grade and treat early (predominantly pre-invasive) cancers. The group is currently focused on early cancer management issues in the Lung, Cervix, Prostate, Breast and Skin.


Radiation Biophysics

Research in the radiation biophysics laboratory in the Department of Integrative Oncology at the BC Cancer Research Centre is focused on improving radiation and drug treatment of solid tumours and also includes studies into the biology and vasculature of solid tumours as well as methods of treating tumours and predicting their response to treatment.

Faculty Engaged: Medical Physics

Name Position Research
Anna Celler Associate Member, Medical Physics Research Field: Nuclear Medical Imaging
Cheryl Duzenli Adjunct Professor, Medical Physics
Nancy Ford Associate Member, Medical Physics Research Field: X-ray imaging, micro-computed tomography, dental x-ray imaging
Topics Include: ***Actively recruiting for this project***
Contrast agent assessment for correlative imaging across different preclinical and specimen imaging modalities (micro-CT, optical projection tomography, etc.):
We are developing techniques to image contrast media with different imaging modalities (x-ray and optical). Using a single contrast media will ensure that the same structures are highlighted in each of the images. We are also working with novel contrast agents containing different metallic nanoparticles to determine the efficacy and time course of these agents.
Shannon Kolind Associate Member, Medical Physics Research Field: Magnetic Resonance Imaging
Topics Include: Biologically-specific MRI techniques, development of new acquisition and analysis methods, applications in clinical reasearch
Piotr Kozlowski Associate Member, Medical Physics Research Field: MRI
Corree Laule Associate Member, Medical Physics Research Field: myelin water imaging, quantitative MRI, T1 and T2 relaxation, brain, spinal cord, myelin, histology, lipids, multiple sclerosis, spinal cord injury, neurological diseases
Alex MacKay Professor, Medical Physics Research Field: Nuclear Magnetic Resonance/ Magnetic Resonance Imaging
Vitali Moiseenko Adjunct Professor, Medical Physics Research Field: BC Cancer Agency
Karl Otto Adjunct Professor, Medical Physics Research Field: Medical Physics
Tony Popescu Adjunct Professor, Medical Physics Research Field: BCCA Vancouver
Arman Rahmim Associate Professor, Medical Physics Research Webpage
Research Field: Molecular imaging, Image Reconstruction, Quantitative Imaging, Machine learning and radiomics, Theranostics
Alexander Rauscher Associate Member, Medical Physics Research Field: Magnetic resonance imaging
Topics Include: quantitative susceptibility mapping, myelin water imaging, neuroscience, multiple sclerosis, concussion
Stefan Reinsberg Associate Professor, Medical Physics Research Field: MR Imaging and Spectroscopy
Topics Include: MRI and MRS in Cancer, Image Method Development
Vesna Sossi Professor, Medical Physics Research Field: Medical Imaging - PET, Positron Emission Tomography Brain Imaging; Multimodality Imaging
Topics Include: Instrumentation, Algorithms, Neurodegeneration, Clinical and Preclinical Imaging
Qing-San Xiang Associate Member, Medical Physics Research Field: Magnetic Resonance Imaging (MRI)
Haishan Zeng Associate Member, Biophysics Research Field: Biomedical Optics/Photomedicine